New mid-stage clinical trial results revealed on Monday showed that Eli Lilly’s experimental drug was effective in helping patients lose as much as 24% of their weight after nearly a year. This marks the most significant reduction seen in the field of obesity treatment thus far.
During the phase two trial, a total of 338 overweight or obese adults were diligently observed and evaluated. They were administered either Retatrutide, a highly effective injection from a leading pharmaceutical company, or a placebo every week with great care and precision.
After 24 weeks, individuals who were administered a 12-milligram dosage of Retatrutide experienced an average weight loss of 41 pounds, which is equivalent to 17.5% of their body weight. Conversely, those who were given the placebo only saw a weight loss of 1.6%.
Patients achieved an outstanding weight loss of 24.2%, equivalent to a remarkable 58 pounds, over 48 weeks. On the other hand, those who were given a placebo merely experienced a meager 2.1% reduction in their body weight within the same timeframe.
According to the researchers conducting the trial, the average weight loss did not reach a plateau even after 48 weeks. This indicates that a longer study might reveal even more promising results. Currently, Eli Lilly is in the process of recruiting patients for the third phase of the trial.
Retatrutide from Eli Lilly is unequivocally the most effective anti-obesity medication to date, according to Michael Weintraub, an endocrinologist at NYU Langone Health. This fact was shared via a post on Twitter.
Eli Lilly’s Mounjaro is highly effective in clinical trials as a weight loss aid for patients diagnosed with type 2 diabetes, with up to 21% weight reduction observed.
Wegovy, a weight loss treatment by Novo Nordisk, has been clinically tested and has demonstrated up to a 15% reduction in body weight.
Retatrutide, developed by Eli Lilly, is a weekly injection that mimics certain gut hormones to regulate appetite, much like Wegovy and Mounjaro.
Wegovy imitates only the hunger-regulating hormone known as GLP-1, whereas Mounjaro imitates both GLP-1 and another hormone named GIP.
Retatrutide can mimic the actions of three essential hormones that regulate hunger: GLP-1, GIP, and glucagon. This substance can significantly alter an individual’s appetite and satisfaction with meals.
Eli Lilly Long (Buy)
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